The 2022 Mercedes-Benz E-Class is available in a choice of three trims: E350, E350 4Matic, and E450 4Matic. Both E350 models are powered by a 2.0-liter turbocharged four-cylinder gas engine producing 255 hp and 273 lb-ft of torque. Power is sent to the rear or all four wheels via a nine-speed automatic transmission. The E450 4MATIC is powered by a turbocharged 3.0-liter inline-six motor producing 362 hp and 369 lb-ft augmented by an EQ Boost mild-hybrid system with 21 hp and 184 lb-ft. All three trim levels share the same feature list, which includes standard LED headlights, 18-inch alloy wheels, a 64-color LED interior lighting system, power-adjustable front seats, a 12.3-inch digital gauge cluster, and a 12.3-inch touchscreen infotainment display with Apple CarPlay and Android Auto. Driver assistance features include automatic high-beam assist, blind-spot monitoring, driver-attention assist, and crosswind assist. There is a lengthy options list that includes top-class leather upholstery choices, adaptive cruise control, ventilated front seats, and a lot more.